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沈宏伟
从事微生物发酵工程的研究。

籍  贯:辽宁省铁岭市

职  称:助理研究员

研究方向:微生物发酵工程

联系电话:0411-84379066

电子信箱:hongweish@dicp.ac.cn

个人简历:
  1997-2001 吉林农业大学 学士学位
  2001-2005 长春大成集团
  2005-2008 大连工业大学 发酵工程 工学硕士学位
  2009-2014 大连理工大学 生物化工 工学博士学位
  2008-   大连化学物理研究所生物技术部1816组

主持科研项目:

1.车用生物燃料技术国家重点实验室开放课题(KFKT2014009),木质纤维素制备生物柴油新型原料油脂发酵过程研究,2015.09-2017.08,5万元,在研,主持

2.国家科技支撑项目(2014BAD02B02),栎类淀粉与秸秆生物质炼制生物柴油及其综合利用产业化示范,2014.01-2016.12,768万元,在研,子课题负责人(70万)

3.大连化学物理研究所青年基金(S201027),二级发酵生产微生物油脂的研究,8万元,2010.03-2011.12,结题,主持

主要发表论文:

 1. Shen HW, Zhang XB, Gong ZW, Wang YN, Yu X, Yang XB, Zhao ZK. “Compositional profiles of Rhodosporidium toruloides cells under nutrient limitation” Appl. Microbiol. Biotechnol. 2017,101(9), 3801–3809.

 2.Gong ZW, Zhou WT, Shen, HW, Yang ZH, Wang GH, Zuo ZY, Hou YL, Zhao ZK. “Co-fermentation of acetate and sugars facilitating microbial lipid production on acetate-rich biomass hydrolysates” Bioresour. Technol, 2016, 207: 102108.

 3. Zhang XB, Shen HW, Yang XB, Wang Q, Yu X, Zhao ZK. “Microbial lipid production by oleaginous yeasts on Laminaria residue hydrolysates” RSC Advances, 2016, 6(32): 2675226756.

 4. Shen HW, Yang XB, Gong ZW, Jin GJ, Zhao ZK. “Prediction of lipid yield and substrate distribution based on consumed C/N ratio” CIESC Journal, 2016, 67(1): 324330.

 5. Gong ZW, Shen HW, Zhou WT, Wang YD, Yang XB, Zhao ZK. “Efficient conversion of acetate into lipids by the oleaginous yeast Cryptococcus curvatusBiotechnol. Biofuels, 2016, 8: 189.

 6. Yang XB; Jin GJ, Wang, YD, Shen HW, Zhao ZK. “Lipid production on free fatty acids by oleaginous yeasts under non-growth conditions” Bioresour. Technol, 2015, 193: 557562.

 7. Wang YD, Gong ZW, Yang, XB, Shen HW, Wang Q, Wang JH, Zhao ZK. “Microbial lipid production from pectin-derived carbohydrates by oleaginous yeasts” Process. Biochem, 2015, 50(7): 10971102.

 8. Zhu ZW, Ding YF, Gong ZW, Yang L, Zhang SF, Zhang CY, Lin XP, Shen HW, Zou HF, Xie ZS, Yang FQ, Zhao XD, Liu PS, Zhao ZK. “Dynamics of the Lipid Droplet Proteome of the Oleaginous Yeast Rhodosporidium toruloidesEukaryot Cell, 2015, 14(3): 252264.

 9. Song YH, Shen HW, YW, Yang XB , Gong ZW , Zhao ZK. “High cell density culture of an engineered yeast strain for sclareol production” Chin J Biotech, 2015, 31(1): 147151.

 10.Yang XB, Jin GJ, Gong ZW, Shen HW, Bai FW, Zhao ZK. “Recycling microbial lipid production wastes to cultivate oleaginous yeasts” Bioresour. Technol. 2015, 175, 91–96.

 11.Yu X,Tian J,Xie HB,Shen HW,Wang Q.“The integrated production of microbial lipids and bio-SiO2 from rice husks by an organic electrolytes pretreatment technology”Bioresour Technol. 2014,153,403–407.

 12.Yang XB, Jin GJ, Gong ZW, Shen HW, Song YH, Bai FW, Zhao ZK. “Simultaneous utilization of glucose and mannose from spent yeast cell mass for lipid production by Lipomyces starkeyi Bioresour Technol. 2014, 158, 383–387.

 13.Yang XB, Jin GJ, Gong ZW, Shen HW, Bai FW, Zhao ZK. “Recycling biodiesel-derived glycerol by the oleaginous yeast Rhodosporidium toruloides Y4 through the two-stage lipid production process” Biochem. Eng. J. 2014, 91(1), 86–91.

 14.Gong ZW, Wang Q, Shen HW, Xie HB, Zhao ZK. “Conversion of biomass-derived oligosaccharides into lipids” Biotechnol. Biofuels 2014, 7, 13.

 15.Shen HW, Gong ZW, Yang XB, Jin GJ, Bai FW, Zhao ZK. “Kinetics of continuous cultivation of the oleaginous yeast Rhodosporidium toruloidesJ. Biotechnol. 2013, 168(1), 85–89

 16.Jin GJ, Zhang YX, Shen HW, Yang XB, Xie HB, Zhao ZK. “Fatty acid ethyl esters production in aqueous phase by the oleaginous yeast Rhodosporidium toruloidesBioresour. Technol. 2013, 150, 266–270.

 17.Huang QT, Wang Q, Gong ZW, Jin GJ, Shen HW, Xiao S, Xie HB, Ye SH, Wang JH, Zhao ZK. “Effects of selected ionic liquids on lipid production by the oleaginous yeast Rhodosporidium toruloidesBioresour. Technol. 2013, 130(1), 339–344.

 18.Gong ZW, Shen HW, Wang Q, Yang XB, Zhao ZK. “Efficient conversion of biomass into lipids by using the simultaneous saccharification and enhanced lipid production process” Biotechnol. Biofuels 2013, 6, 36.

 19. Zhu ZW, Zhang SF, Liu HW, Shen HW, Lin XP, Yang F, Zhou YJ, Jin GJ, Ye ML, Zou HF& Zhao ZB.K, “A multi-omic map of the lipid-producing yeast Rhodosporidium toruloides” Nature Communications, 2012, 3, 112.

 20. Gong ZW, Wang Q, Shen HW, Hu CM, Jin GJ, Zhao ZK. “Co-fermentation of cellobiose and xylose by Lipomyces starkeyi for lipid production” Bioresource Technology. 2012, 117(1), 20–24.

 21. Xie HB, Shen HW, Gong ZW, Wang Q, Zhao ZK, Bai FW. “Enzymatic hydrolysates of corn stover pretreated by the N-methylpyrrolidone/ionic liquids solution for microbial lipid production” Green Chem. 2012, 14(4), 1202–1210.

 22. Jin GJ, Yang F, Hu CM, Shen HW, Zhao ZK. “Enzyme-assisted extraction of lipids directly from the culture of the oleaginous yeast Rhodosporidium toruloides” Bioresour.Technol. 2012, 111, 378–382.

 23. Cao XF, Xie HB, Wu ZL, Shen HW, Jing B,“Phase-switching Homogeneous Catalysis for Clean Production of Biodiesel and Glycerol from Soybean and Microbial Lipids” ChemCatChem, 2012, 4, 1272-1278.

 24. 沈宏伟;靳国杰;胡翠敏;龚志伟;白凤武;赵宗保.“恒化培养中稀释率和碳氮比对圆红冬孢酵母油脂积累的影响” 生物工程学报 2012, 28(1), 57–65.

 25. Hu CM, Wu SG, Wang Q, Jin GJ, Shen HW, Zhao ZK. “Simultaneous utilization of glucose and xylose for lipid production by Trichosporon cutaneum Biotechnol. Biofuels 2011, 4, 25.

 26. Zhao X, Hu CM, Wu SG, Shen HW, Zhao ZK. “Lipid production by Rhodosporidium toruloides Y4 using different substrate feeding strategies” J. Ind. Microbiol. Biotechnol. 2011, 38(5), 627–632.

 27. Lin JT, Shen HW, Tan HD, Zhao X, Wu SG, Hu CM, Zhao ZK. “Lipid production by Lipomyces starkeyi cells in glucose solution without auxiliary nutrients” J. Biotechnol. 2011, 152(4), 184–188.

 28. Wu SG, Zhao X, Shen HW, Wang Q, Zhao ZK.“Microbial lipid production by Rhodosporidium toruloides under sulfate-limited conditions” Bioresour. Technol. 2011,102(2), 1803–1807.

 29. 林金涛;沈宏伟;张泽会;胡翠敏;靳国杰;谭海东;赵宗保. “圆红冬孢酵母两阶段培养法生产微生物油脂” 生物工程学报 2010, 26(7), 997–1002.

 30. Zhao ZK, Zhao X, Hu CM, Shen HW, Wu SG. Towards industrial lipid production using oleaginous yeasts. New Biotech. 2009, 25(Suppl. 1), S233.

授权专利:

1. 赵宗保, 吴思国, 胡翠敏, 沈宏伟. 一种产油微生物培养的方法. 中国专利,专利号: 200910219980.3, 授权日期: 2014.02.26.

2. 赵宗保, 林金涛, 沈宏伟, 吴思国. 一种产油微生物的培养方法. 中国专利,专利号: 201010202215.3, 授权日期: 2014.05.14

3. 赵宗保, 龚志伟, 沈宏伟. 一种产油微生物的培养方法. 中国专利,专利号: 201210020546.4, 授权日期: 2015.04.29


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